Moderate -0.5 This is a straightforward application of Poisson approximation to binomial with clearly stated parameters (n=150000, p=1/50000, giving λ=3). The calculation requires finding P(X>2)=1-P(X≤2) using standard Poisson tables or formula. While it involves Further Maths content, it's a routine textbook exercise with no conceptual challenges beyond recognizing when to use the approximation.
1 On average, 1 in 50000 people have a certain gene.
Use a suitable approximating distribution to find the probability that more than 2 people in a random sample of 150000 have the gene.
1 On average, 1 in 50000 people have a certain gene.\\
Use a suitable approximating distribution to find the probability that more than 2 people in a random sample of 150000 have the gene.\\
\hfill \mbox{\textit{CAIE S2 2020 Q1 [3]}}